Bupivacaine Hydrochloride and Epinephrine Bitartrate Injection Shortage Update

What’s in Shortage

Bupivacaine Hydrochloride and Epinephrine Bitartrate Injection (Brand names: SENSORCAINE, SENSORCAINE MPF) is currently listed in shortage. This medication is an injection used within the therapeutic category of Anesthesia. While several presentations remain available, the FDA classifies the overall status of this drug as a “Current” shortage.

Which Manufacturers Are Affected

Fresenius Kabi USA, LLC

• Status: Limited Availability
• Contact: 888-386-1300
• Availability Details:
  • Unavailable: Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-462-31).
  • Available: The following presentations are currently available, though the manufacturer recommends checking wholesalers for inventory:
    • Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-463-57)
    • Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (NDC 63323-468-37)
    • Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (NDC 63323-468-17)
    • Sensorcaine, Injection, 7.5 mg/1 mL; .005 mg/1 mL (NDC 63323-460-37)
    • Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-462-17)
    • Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (NDC 63323-461-57)
    • Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (NDC 63323-462-37)

Why There’s a Shortage

No specific reason for this shortage was provided in the source data.

What Patients Should Do

If you are scheduled for a procedure requiring anesthesia, please be aware of this supply update. Patients should:

• Consult with their healthcare provider or surgeon regarding the availability of specific medications for their procedure.
• Speak with a pharmacist for the most current local inventory information.
• Contact the manufacturer, Fresenius Kabi USA, at 888-386-1300 for specific product inquiries.

Disclaimer: Patients should always consult their healthcare provider for medical advice and to discuss alternative treatment options.

Source

Attribution: FDA Drug Shortage Database Initial Posting Date: 02/20/2018 Last Updated: 02/05/2026