Bupivacaine Hydrochloride Injection Shortage: FDA Updates Availability and Manufacturer Status

What’s in Shortage

Bupivacaine Hydrochloride Injection, a medication used for anesthesia, is currently listed in shortage. This includes brand-name versions such as Sensorcaine and Sensorcaine MPF. The shortage affects various strengths of the injection, including 2.5 mg/1 mL, 5 mg/1 mL, and 7.5 mg/1 mL presentations.

Which Manufacturers Are Affected

Two primary manufacturers are listed in the FDA database with the following statuses:

• Eugia US LLC (888-238-7880): All listed presentations of Bupivacaine Hydrochloride Injection (2.5 mg/1 mL, 5 mg/1 mL, and 7.5 mg/1 mL) are currently Available. The manufacturer advises checking with wholesalers for current inventory.
• Fresenius Kabi USA, LLC (888-386-1300): This manufacturer reports mixed availability for its Sensorcaine products:
  • Unavailable: Sensorcaine 2.5 mg/1 mL (NDC 63323-464-31) and Sensorcaine 5 mg/1 mL (NDC 63323-466-31).
  • Available: Various other presentations of Sensorcaine in 2.5 mg/1 mL, 5 mg/1 mL, and 7.5 mg/1 mL strengths remain available. Wholesalers should be contacted for inventory updates.

Why There’s a Shortage

According to the FDA, the primary reason for the current shortage is a demand increase for the drug.

What Patients Should Do

If you are scheduled for a procedure requiring anesthesia, please be aware of this supply update. Patients should:

• Consult with their healthcare provider or surgeon regarding the availability of medications for their specific procedure.
• Speak with a pharmacist if they have questions about local supply.
• Contact the manufacturers directly using the phone numbers provided above for the most recent distribution information.

Disclaimer: Patients should always consult their healthcare provider for medical advice, diagnosis, and treatment options. Do not make changes to your medical care without professional consultation.

Source

Information provided by the FDA Drug Shortage Database.

• Initial Posting Date: 02/20/2018
• Last Updated: 02/05/2026